Long-Lasting Frown Line Treatment
DAXXIFY® at Skin365
We’re proud to be one of the first providers to offer DAXXIFY®, the only FDA-approved, long-lasting frown line treatment made in the United States. Created and manufactured in California, DAXXIFY® is revolutionizing wrinkle treatments with its exclusive, peptide-powered formula.
If you’re searching for an effective, longer-lasting alternative to Botox® or Dysport®, DAXXIFY® may be the solution you’ve been waiting for.
At Skin365, our expert injectors specialize in advanced, natural-looking results.

What Makes DAXXIFY® Different?
Unlike traditional wrinkle relaxers, DAXXIFY® is powered by a novel peptide—making it the only frown line treatment that does not use human or animal byproducts as stabilizers.
✨ Benefits of DAXXIFY® at Skin365:
- FDA-approved to smooth moderate to severe frown lines between the brows
- Peptide-powered technology for leaner, more effective results
- Long-lasting outcomes – average of 6 months, up to 9 months for some patients
- Fast-acting – noticeable results as soon as the next day, typically within 2 days
In clinical studies, 50% of patients still had little to no frown lines 6 months after treatment.
How DAXXIFY® Compares to Botox® and Dysport®
All frown line treatments require an ingredient to stabilize botulinum toxin A:
Botox® Cosmetic uses human serum albumin (HSA), a blood product
Dysport® uses HSA and cow’s milk protein
DAXXIFY® is different—it’s the only treatment stabilized with a peptide, avoiding human and animal
byproducts altogether
This unique peptide formulation also allows more of the active ingredient to enter nerve cells, giving you smoother results that last longer while enhancing skin texture.
Smooth. Natural. Long-lasting.
Results
Generally, begin to see results within 1 – 3 days after treatment, lasts up to 6 months
Downtime
Little to no downtime after treatment
Possible Side Effects
Bruising at site, headache, injection site pain, eyelid drooping, eyelid swelling
Best For
Moderate to severe wrinkles and frown lines between the eyebrows